TIF1 alpha (TRIM24) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24.
Formulation	TRIM24 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TRIM24 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	112 kDa
Gene Name	tripartite motif containing 24
Database Link	NP_056989 Entrez Gene 8805 Human UniProt ID O15164
Background	TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC).
Synonyms	hTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.