AP3S1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	AP3S1 antibody was raised against a 19 amino acid synthetic peptide near the center of human AP3S1.
Formulation	AP3S1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	AP3S1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	adaptor related protein complex 3 sigma 1 subunit
Database Link	NP_001275 Entrez Gene 11777 MouseEntrez Gene 302290 RatEntrez Gene 1176 Human UniProt ID Q92572
Background	AP3S1 Antibody: AP3S1 belongs to the adaptor complexes 3 (AP3) small subunit family which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3 is an heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP3S1 Interacts with AGAP1 and may play an important role in carcinoma.
Synonyms	CLAPS3; Sigma3A
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Lysosome

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