Esrp1 Mouse Monoclonal Antibody [Clone ID: 27H12]
CNY 8,303.00
CNY 300.00
CNY 1,430.00
CNY 7,106.00
Specifications
Product Data | |
Clone Name | 27H12 |
Applications | WB |
Recommend Dilution | ELISA: 1:750,000, WB: 1:1000 |
Reactivity | Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Anti-Esrp-1 was produced by repeated immunizations of full length recombinant mouse Esrp-1 fusion protein. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | epithelial splicing regulatory protein 1 |
Database Link | |
Synonyms | FLJ20171; RBM35A; RMB35A |
Note | Epithelial splicing regulatory protein 1 (Esrp-1) is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2, and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). EsrpP-1 acts by directly binding specific sequences in mRNAs. It binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. |
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