BIN3 Mouse Monoclonal Antibody [Clone ID: 3A4]

Specifications

Product Data
Clone Name	3A4
Applications	WB
Recommend Dilution	ELISA: 1:5000-1:50000, WB: 1:500-1:1500, IP: 10-100 uL
Reactivity	Mouse, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Anti-BIN3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with a full legnth human BIN3 recombinant protein followed by hybridoma development.
Formulation	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	bridging integrator 3
Database Link	NP_061158 Entrez Gene 57784 MouseEntrez Gene 55909 Human UniProt ID Q9NQY0
Synonyms	MGC14978
Note	BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking. In humans, Bin3 maps to chromosome 8p21.3, a region widely implicated in cancer suppression that is often deleted in non–Hodgkin’s lymphomas and various epithelial tumors. Study in mouse suggests that homozygous inactivation of Bin3 causes cataracts and an increased susceptibility to lymphomas during aging.
Reference Data

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