IRS1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1:500~1:3000, IF: 1:100~1:500, ELISA: 1:20000
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 312 (A-T-SP-P-A)
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	insulin receptor substrate 1
Database Link	NP_005535 Entrez Gene 16367 MouseEntrez Gene 25467 RatEntrez Gene 3667 Human UniProt ID P35568
Synonyms	HIRS-1
Note	IRS-1 (Phospho-Ser312) antibody detects endogenous levels of IRS-1 only when phosphorylated at serine 312.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus

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