Natriuretic Peptide Receptor C (NPR3) Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1-3ug/ml
Reactivity	Human, Mouse, Rat, Dog, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-HRELREDSIRSHFS, from the C Terminus of the protein sequence according to NP_000899.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	natriuretic peptide receptor 3
Database Link	NP_000899 Entrez Gene 18162 MouseEntrez Gene 25339 RatEntrez Gene 612616 DogEntrez Gene 4883 Human UniProt ID P17342
Background	This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPRC
Reference Data
Protein Families	Druggable Genome, Transmembrane

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