Rhodopsin (RHO) Mouse Monoclonal Antibody [Clone ID: 4D2]

Specifications

Product Data
Clone Name	4D2
Applications	IF
Recommend Dilution	ICC, IHC, IP, WB, ELISA
Reactivity	Human, Mouse, Rat, Bovine, Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Bovine Rhodopsin
Formulation	TBS, 50% glycerol, 0.09% sodium azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	rhodopsin
Database Link	NP_000530 Entrez Gene 24717 RatEntrez Gene 212541 MouseEntrez Gene 6010 Human UniProt ID P08100
Background	Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq]
Synonyms	CSNBAD1; OPN2; RP4
Reference Data
Protein Families	Druggable Genome, Transmembrane

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