Parkin (PARK2) Rabbit Polyclonal Antibody

CAT#: TA309210

Rabbit Anti-Parkin (Ser378) Antibody (Phospho-Specific)



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CNY 5,643.00


货期*
5周

规格
    • 100 ul

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Transient overexpression lysate of Parkinson disease (autosomal recessive, juvenile) 2, parkin (PARK2), transcript variant 2
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:1000
Reactivity Human
Modifications Phospho-specific
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser378 conjugated to KLH
Formulation 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification Affinity Purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 52 kDa
Gene Name parkin RBR E3 ubiquitin protein ligase
Background The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq]
Synonyms AR-JP; LPRS2; PDJ; PRKN
Reference Data
Protein Pathways Parkinson's disease, Ubiquitin mediated proteolysis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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