ING5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:500-1:3000
Reactivity	Human, Rat, Xenopus, Chicken, Bovine, Rhesus Monkey, X. tropicalis, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 46 and 142 of ING5 (Uniprot ID#Q8WYH8)
Formulation	1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	28 kDa
Gene Name	inhibitor of growth family member 5
Database Link	NP_115705 Entrez Gene 66262 MouseEntrez Gene 363292 RatEntrez Gene 84289 Human UniProt ID Q8WYH8
Background	The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq]
Synonyms	p28ING5
Note	Seq homology of immunogen across species: Mouse (100%), Rat (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)
Reference Data
Protein Families	Druggable Genome

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