DYRK3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Cow
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment contain a sequence corresponding to a region within amino acids 243 and 532 of Dyrk3 (Uniprot ID#O43781)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	64 kDa
Gene Name	dual specificity tyrosine phosphorylation regulated kinase 3
Database Link	NP_003573 Entrez Gene 226419 MouseEntrez Gene 304775 RatEntrez Gene 8444 Human UniProt ID O43781
Background	This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Synonyms	DYRK5; hYAK3-2; RED; REDK
Note	Seq homology of immunogen across species: mouse (92%), Rat (94%), cow (95%)
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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