Endothelin 3 (EDN3) Rabbit Polyclonal Antibody

CAT#: TA308462

Rabbit polyclonal antibody to Endothelin 3 (endothelin 3)



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CNY 6,281.00


货期*
5周

规格
    • 100 ul

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Transient overexpression lysate of endothelin 3 (EDN3), transcript variant 1
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Specifications

Product Data
Applications WB
Recommend Dilution WB:1:500-1:3000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 217 of ET-3 (Uniprot ID#P14138)
Formulation 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 25 kDa
Gene Name endothelin 3
Background The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq]
Synonyms ET-3; ET3; HSCR4; PPET3; WS4B
Reference Data
Protein Families Druggable Genome, Secreted Protein
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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