RAIDD (CRADD) Rabbit Polyclonal Antibody

CAT#: TA305944

Rabbit Polyclonal RAIDD Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution WB: 1 ug/mL, IHC: 10 ug/mL
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen RAIDD antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human RAIDD. The immunogen is located within the last 50 amino acids of RAIDD.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Antibody is DEAE purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name CASP2 and RIPK1 domain containing adaptor with death domain
Background Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1,RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.
Synonyms DP5; HARAKIRI
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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