XPNPEP1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 0.3-1 µg/ml.
Reactivity	Human, Mouse, Rat, Cow, Pig, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-LIRETQPISKQH, from the C-Terminus of the protein sequence according to NP_065116.2; NP_001161076.1.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Database Link	NP_001161076 Entrez Gene 170750 MouseEntrez Gene 170751 RatEntrez Gene 486880 DogEntrez Gene 7511 Human UniProt ID Q9NQW7
Background	X-prolyl aminopeptidase (EC 3.4.11.9) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-prolyl aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of X-prolyl aminopeptidase results in excretion of large amounts of imino-oligopeptides in urine (Blau et al., 1988 [PubMed 3141711]). [supplied by OMIM]
Synonyms	APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1
Reference Data
Protein Families	Druggable Genome, Protease

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