OGT Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:64,000. WB: 0.05-0.2µg/ml.An
Reactivity	Mouse, Rat, Human, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-YEHPKDLKLSDGR, from the internal region of the protein sequence according to NP_858058.1; NP_858059.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	120561 Da
Gene Name	O-linked N-acetylglucosamine (GlcNAc) transferase
Database Link	NP_858058 Entrez Gene 26295 RatEntrez Gene 108155 MouseEntrez Gene 480955 DogEntrez Gene 8473 Human UniProt ID O15294
Background	O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Synonyms	HRNT1; O-GLCNAC
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, O-Glycan biosynthesis

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