14 3 3 gamma (YWHAG) Mouse Monoclonal Antibody [Clone ID: KC21]

Specifications

Product Data
Clone Name	KC21
Applications	ICC/IF, Simple Western, WB
Recommend Dilution	Simple Western: 1:12.5, Immunocytochemistry/ Immunofluorescence: 1:500, Western Blot: 1:1000-1:3000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	This antibody was raised against an N-terminal fragment of human 14-3-3 gamma where the N-terminal Val was acetylated.
Formulation	PBS with 0.05% Sodium Azide
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
Database Link	NP_036611 Entrez Gene 7532 Human UniProt ID P61981
Background	14-3-3 proteins are present as multigene families in most organisms. Signal-induced phosphorylation has the ability to change protein function. Sometimes, however, phosphorylation is not enough to change a protein's function. 14-3-3 proteins play an important role of bringing signal transduction to completion. They regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints.
Synonyms	14-3-3GAMMA; PPP1R170
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

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