Macrophage Scavenger Receptor I (MSR1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, WB
Recommend Dilution	Western Blot: 2 ug/mL, Immunocytochemistry/ Immunofluorescence: 1:50 - 1:200
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to an internal portion of the human MSR protein sequence (between residues 300-400). UniProt P21757
Formulation	Tris-glycine and 150mM NaCl and 0.05% sodium azide
Purification	peptide affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	macrophage scavenger receptor 1
Database Link	NP_619729 Entrez Gene 20288 MouseEntrez Gene 4481 Human UniProt ID P21757
Background	Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).
Synonyms	CD204; phSR1; phSR2; SCARA1; SR-A; SRA
Reference Data
Protein Families	Druggable Genome, Transmembrane

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