Nkx3.1 (NKX3-1) Mouse Monoclonal Antibody

Specifications

Product Data
Applications	IHC, IP, WB
Recommend Dilution	Immunohistochemistry: 1:100, Immunoprecipitation: 1:10-1:500, Western Blot: 2 ug/ml, Immunohistochemistry-Paraffin: 1:100, Immunohistochemistry-Frozen: 1:100, Knockdown Validated
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	This antibody was raised against human Nkx3.1 full-length protein producced in bacteria as a hexahistidine-tagged protein.
Formulation	PBS, pH 7.4 and 0.1% sodium azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NK3 homeobox 1
Database Link	NP_006158 Entrez Gene 18095 MouseEntrez Gene 4824 Human UniProt ID Q99801
Background	Nkx3.1 is a transcription factor that may play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in the prostate. It has been thought to be one of the target genes of the 8p21 loss of heterozygosity, common in prostate cancer. But neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.
Synonyms	BAPX2; NKX3; NKX3.1; NKX3A
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Pathways in cancer, Prostate cancer

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