PDK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, WB
Recommend Dilution	Immunocytochemistry/ Immunofluorescence: 1:1000-1:2000, Western Blot: 2 ug/ml
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to a C-Terminal portion of the human PDK1 protein sequence (between residues 350-436). [Swiss-Prot Q15118]
Formulation	Tris-glycine, 150mM NaCl and 0.05% sodium azide
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	pyruvate dehydrogenase kinase 1
Database Link	NP_002601 Entrez Gene 5163 Human UniProt ID Q15118
Background	Pyruvate dehydrogenase kinase isoform 1 (PDK1) inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Synonyms	isoenzyme 1; isozyme 1; mitochondrial pyruvate dehydrogenase kinase isoenzyme 1; pyruvate dehydrogenase kinase
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Fc epsilon RI signaling pathway, Neurotrophin signaling pathway, T cell receptor signaling pathway

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