FLIP (CFLAR) (Long Form) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	Western blot: 1/500 - 1/2000. Immunocytochemistry.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide at C-terminus of human FLIPL
Specificity	This antibody recognises the 55kD FLIPL protein, a FLICE inhibitory protein.
Formulation	PBS containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Ion exchange chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CASP8 and FADD like apoptosis regulator
Database Link	Entrez Gene 8837 Human UniProt ID O15519
Background	FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors. FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by this antibody.
Synonyms	c-FLIP, CLARP, MRIT, CASH, FLAME-1, CASP8AP1, Usurpin
Reference Data

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