DR3 (TNFRSF25) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	Western blot: 1:500 - 1:1000. Immunocytochemistry.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide from extracellular domain of human DR3
Specificity	This antibody recognises a 59kD apoptosis related protein designated DR3 (death receptor 3).
Formulation	PBS containing 0.02% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Ion exchange chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	tumor necrosis factor receptor superfamily member 25
Database Link	Entrez Gene 8718 Human UniProt ID Q93038
Background	DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95). The receptor for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, a functionally induces apoptosis and NF-KB activation.
Synonyms	APO3, DDR3, TNFRSF12, WSL, WSL1, Apo-3, AIR, Death receptor 3, LARD, Protein WSL, Protein WSL-1
Reference Data

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