Nucleophosmin (NPM1) (81-294) Mouse Monoclonal Antibody [Clone ID: 5E3]

Specifications

Product Data
Clone Name	5E3
Applications	ELISA, FC, IF, IHC, WB
Recommend Dilution	ELISA. Western blot (1/1,000-1/2,000). Immunohistochemistry on paraffin-embedded sections (1/100). Immunocytochemistry / Immonofluorescence. Flow Cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human NPM (81-294 aa) purified from E. coli
Specificity	The antibody recognizes Human NPM at aa 81-294. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Database Link	Entrez Gene 4869 Human UniProt ID P06748
Background	Nucleophosmin (NPM; also known as B23, NO38, or numatrin) is a nucleolar phosphoprotein that binds the tumor suppressors p53 and p19Arf and is thought to be indispensable for ribogenesis, cell proliferation, and survival after DNA damage. Nucleophosmin is upregulated in many cancer cells.
Synonyms	NPM, NPM1, Numatrin
Reference Data

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