Geminin (GMNN) Mouse Monoclonal Antibody [Clone ID: 2H7]

Specifications

Product Data
Clone Name	2H7
Applications	ELISA, WB
Recommend Dilution	Western blot (1/500-1/1,000; recommended starting dilution 1/500). ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human Geminin (aa 1-209) purified from E. coli
Specificity	This antibody is specific for Geminin.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	geminin, DNA replication inhibitor
Database Link	Entrez Gene 51053 Human UniProt ID O75496
Background	Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.
Synonyms	GMNN
Reference Data

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