AK3 Mouse Monoclonal Antibody [Clone ID: SJB3-36]

Specifications

Product Data
Clone Name	SJB3-36
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1:500 - 1:2,000), recommended starting dilution is 1:1,000. Immunohistochemistry (1:100).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human AK3 (adenylaste kinase isozyme 3) purified from E. coli
Specificity	This antibody (clone SJB3-36) has the specificity against AK3.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	adenylate kinase 3
Database Link	Entrez Gene 50808 Human UniProt ID Q9UIJ7
Background	Adenylate kinase (AK; adenosine triphosphate-adenosine monophosphate [ATP-AMP] phospho-transferase, EC 2.7.4.3) is a ubiquitous monomeric enzyme involved energy metabolism of prokaryotic and eukaryotic cells. Three isozymes (AK1, AK2 and AK3) are characterized in vertebrates. AK1 is present in the cytosol of skeletal muscle, brain, and erythrocyte, while AK2 is localized in the intermembrane space of mitochondria of liver, kidney, spleen and heart. AK3, called GTP:AMP phosphotransferase, exists in the mitochondrial matrix of liver and heart. These isozymes contribute to homeostasis of the adenine nucleotide composition in the cell.
Synonyms	AK3L1, AK6, AKL3L
Reference Data

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