ICAM3 Mouse Monoclonal Antibody [Clone ID: MEM-171]

CAT#: SM3028P

ICAM3 mouse monoclonal antibody, clone MEM-171, Purified



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CNY 3,140.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name MEM-171
Applications FC, IP
Recommend Dilution Flow cytometry: 4 µg/ml.
Immunoprecipitation.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human granulocytes
Specificity The antibody recognizes an epitope in the D2 domain of human CD50 (ICAM-3).
Formulation Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography; purity: > 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name intercellular adhesion molecule 3
Background CD50 is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.
Synonyms ICAM-3, ICAM-R, CDw50
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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