Cd8a Mouse Monoclonal Antibody [Clone ID: OX-8]
CAT#: SM259R
Cd8a mouse monoclonal antibody, clone OX-8, PE
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CNY 6,861.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | OX-8 |
Applications | FC |
Recommend Dilution | Flow Cytometry: Neat - 1/10; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl. |
Reactivity | Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Rat thymocyte membrane glycoproteins. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line. |
Specificity | This antibody recognises the CD8 alpha cell surface antigen, expressed by a subset of T lymphocytes, most thymocytes and the majority of NK cells. Clone MRC OX-8 is suitable for use in in vitro blocking studies. We recommend the use of SM259A for this purpose. This clone has been described reacting with paraffin-embedded material following PLP Fixation (periodatelysine paraformaldehyde) |
Formulation | PBS, pH7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: PE State: Lyophilized purified IgG Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Restore with 1 ml distilled water |
Purification | Affinity chromatography on Protein G |
Conjugation | PE |
Storage Condition | Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | CD8a molecule |
Database Link | |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
Synonyms | CD8 alpha chain, CD8A, MAL |
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