DC SIGN (CD209) Mouse Monoclonal Antibody [Clone ID: MR-1]
CAT#: SM2219R
DC SIGN (CD209) mouse monoclonal antibody, clone MR-1, PE
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CNY 6,369.00
货期*
4周
规格
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Specifications
Product Data | |
Clone Name | MR-1 |
Applications | FC |
Recommend Dilution | Flow Cytometry (Neat-1/10): Use 10 µl of the suggested working dilution to label 10e6 cells in 100 µl. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Immature myeloid monocyte-derived dendritic cells (MDDCs). Spleen cells from immunised Balb/c mice were fused with cells of the Mouse SP2/0-Ag14 myeloma cell line. |
Specificity | This antibody recognises human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 which is also known as CD209. Clone MR-1 is reported to partially block the functional activity of DC-SIGN. We recommend the use of SM2219LE for this purpose. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Restore with 1 ml distilled water |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G. |
Conjugation | PE |
Storage Condition | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | CD209 molecule |
Database Link | |
Background | CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's. |
Synonyms | DCSIGN1, DCSIGN, DC-SIGN1, CLEC4L, Dendritic Cell Marker |
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