ICAM2 Rat Monoclonal Antibody [Clone ID: mIC2/4 (3C4)]

Specifications

Product Data
Clone Name	mIC2/4 (3C4)
Applications	FC, FN, IP
Recommend Dilution	Flow Cytometry: 1/50 - 1/200; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl. Immunoprecipitation. Functional Assays.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	COS cells transfected with murine ICAM-2. Spleen cells from immunised Lewis rats were fused with cells of the Mouse P3X63Ag8.653 myeloma cell line.
Specificity	This antibody recognises intercellular adhesion molecule-2 (ICAM-2), also known as CD102. Clone mIC2/4 is reported to inhibit interactions between CD102 and LFA-1.
Formulation	PBS, pH7.4 State: Low Endotoxin State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	intercellular adhesion molecule 2
Database Link	UniProt ID P13598
Background	Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1. Reports suggest that CD102 may play a role in lymphocyte re-circulation and T-cell activation.
Synonyms	ICAM-2
Note	Endotoxin Level: less than 0.01 EU/µg
Reference Data

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