Rat Lambda light chain Mouse Monoclonal Antibody [Clone ID: MARL-15]

CAT#: SM2096P

Rat Lambda light chain mouse monoclonal antibody, clone MARL-15, Purified



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CNY 5,951.00


货期*
4周

规格
    • 250 ug

Product images

Specifications

Product Data
Clone Name MARL-15
Applications ELISA, IHC, WB
Recommend Dilution ELISA.
Western Blot: 1/500-1/1000.
Immunohistochemistry on Frozen Sections.
Reactivity Rat
Host Mouse
Clonality Monoclonal
Immunogen Rat lambda light chain.
Specificity This antibody recognizes immunoglobulin lambda light chain. This antibody shows no cross-reactivity to Ig heavy chains or to kappa light chain.
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide
State: Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Background All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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