IL1B1 Mouse Monoclonal Antibody [Clone ID: DF8]

Specifications

Product Data
Clone Name	DF8
Applications	WB
Recommend Dilution	Western Blot: 1-5 µg/ml.
Reactivity	Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Porcine IL-1 beta.
Specificity	This antibody is specific for Interleukin-1 beta (IL-1 beta).
Formulation	PBS without stabilizer and preservative State: Azide Free State: Liquid purified IgG fraction from Tissue Culture Supernatant
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Database Link	UniProt ID P26889
Background	Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence. IL-1 beta is principally expressed by macrophages, and plays an important immunomodulatory role in the porcine immune response.
Synonyms	IL-1 beta, IL1B, IL1 beta, IL1F2, Catabolin
Reference Data

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