MHC Class II DQ/DR (polymorphic) Mouse Monoclonal Antibody [Clone ID: 49.1]

Specifications

Product Data
Clone Name	49.1
Applications	FC
Recommend Dilution	Flow Cytometry: 1/10; Use 10µl of the suggested working dilution to label 1 x 10e6 cells in 100µl.
Reactivity	Sheep
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognises a polymorphic epitope on MHC class II DQ and DR molecules. In recent work, this clone was found to recognise MHC class II transfectants DQ - T28.1. DR - T8.1. DR - T31.3, but not DQ - T26.2 (Ballingall, K. et al. 1995)
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin Label: FITC State: Liquid purified IgG Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Background	The expression of ovine MHC class II molecules is restricted to B cells, activated T cells, monocytes, macrophages, dendritic cells and some endothelial and epithelial cells.
Reference Data

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