Itga2b Rat Monoclonal Antibody [Clone ID: MWReg30]

Specifications

Product Data
Clone Name	MWReg30
Applications	FC, IHC, IP
Recommend Dilution	Flow cytometry (1/50-1/100): Use 10 µl to label 10e6 cells in 100 µl. Immunohistochemistry on Frozen Sections. Immunoprecipitation.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	This antibody recognizes the integrin alpha IIb subunit CD41. Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo (Nieswandt et al., 1999). SM2035A is recommended for use in functional studies.
Formulation	PBS, containing 0.09% Sodium Azide as preservative. State: Aff - Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	integrin alpha 2b
Database Link	Entrez Gene 16399 Mouse UniProt ID Q9QUM0
Background	CD41, a ~125 kDa single pass type 1 transmembrane glycoprotein, is expressed on platelets, megakaryocytes, mast cells and hematopoietic progenitors and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.
Synonyms	Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb
Reference Data

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