Influenza A H3N2 (Matrix Protein M1) Mouse Monoclonal Antibody [Clone ID: GA2B]

Specifications

Product Data
Clone Name	GA2B
Applications	IF, WB
Recommend Dilution	Western Blot. Immunofluorescence: 1/100.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Influenza A / Puerto Rico / 8 / 34 (H1N1) and A/Bangkok / 1 / 79 (H3N2) viruses. Spleen cells from immunised BALB/c mice were fused with cells of the P3 Ag8.653 mouse myeloma cell line.
Specificity	This antibody recognises an epitope within the Influenza A matrix protein. This antibody can be used in influenza A IFA typing in conjunction with AM01375PU-N (clone AA5H).
Formulation	PBS, pH 7.5 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction (> 90% pure by SDS-PAGE).
Concentration	lot specific
Purification	Affinity Chromatography on Protein A.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Influenza virus type A matrix protein, also known as M1, is composed of a 252 amino acid sequence and is type-specific in influenza viruses. It is located inside the viral lipid envelope and plays a key role in virus assembly and replication. M1 can be isolated from particles by removing the envelope with detergents and reducing the pH to 4.0. Influenza viruses are a common and widely spread infectious agent. Like many other viruses, influenza virus are constantly undergoing mutations and thereby avoiding the immune system. The Influenza A Virus M proteins form a continuous shell on the inner side of the lipid bilayer, maintaining the structural integrity of the virus particle through hydrophobic interactions.
Synonyms	Seasonal Flu H3N2
Reference Data

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