CD49b (ITGA2) Mouse Monoclonal Antibody [Clone ID: 31H4]

CAT#: SM1739P

CD49b (ITGA2) mouse monoclonal antibody, clone 31H4, Purified



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CNY 6,116.00


货期*
4周

规格
    • 200 ug

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Specifications

Product Data
Clone Name 31H4
Applications ELISA, FC, IP
Recommend Dilution Flow cytometry: 1/25 - 1/50;
Immunoprecipitation: 25 - 50 µg/ml.
ELISA: 10 µg/ml.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Purified human beta1 integrin preparation from HT1080 fibrosarcoma cell extract. Spleen cells from immunised BALB/c mice were fused with cells of the X63/Ag8.653 mouse myeloma cell line.
Specificity 31H4 has been identified as being capable of immunoprecipitating the integrin a2 subunit from cell lines surface labelled with 125I. It has been confirmed specific to a2 by relative expression of antigen on various cell lines by flow cytometry, and recognition of affinity purified a2b1 in dot blots.
Formulation PBS, pH7.4 containing 0.09% Sodium Azide
State: Purified
State: Liquid purified IgG
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name integrin subunit alpha 2
Background Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.
Synonyms Integrin alpha-2, ITGA-2, VLA-2 alpha, VLA2, GPIa, Collagen Receptor
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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