MUC2 Mouse Monoclonal Antibody [Clone ID: 996/1]

Specifications

Product Data
Clone Name	996/1
Applications	FC, IHC, WB
Recommend Dilution	Western Blot. Flow Cytometry (Membrane permeabilization is required). Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: This product does not require protein digestion pre-treatment of paraffin sections and does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Positive Control: Normal colon Tissue.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	MUC2 tandem repeat peptide. Spleen cells from immunised Balb/c mice were fused with cells of a mouse NSO myeloma cell line.
Specificity	This antibody recognises the MUC2 mucin, and shows no cross-reactivity with MUC1, MUC3 or MUC4 mucins. In tissue sections SM1709 recognises colon, liver and prostate tissues strongly. The antibody recognises malignant colonic mucosa as well as normal mucosa.
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	mucin 2, oligomeric mucus/gel-forming
Database Link	Entrez Gene 4583 Human UniProt ID Q02817
Background	MUC2 expression is detected in such human tissues as normal colon, breast, prostate, salivary gland and in gastrointestinal, colonic, breast and prostate neoplasia. This antibody labels MUC2 in normal colon and colonic carcinomas where it produces intense perinuclear staining in goblet cells. It also reacts with normal and neoplastic breast tissues and with prostate adenocarcinoma.
Synonyms	MUC-2, MUC2, SMUC, Intestinal mucin-2
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.