CD45 Mouse Monoclonal Antibody [Clone ID: CA12.10C12]
CAT#: SM1581
CD45 mouse monoclonal antibody, clone CA12.10C12, Supernatant
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CNY 6,713.00
货期*
4周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Clone Name | CA12.10C12 |
Applications | FC, IHC |
Recommend Dilution | Flow Cytometry. Immunohistochemistry on frozen sections. |
Reactivity | Canine |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antiboyd recognises the homologue of CD45. Clone CA12.10C12 recognises a glycoprotein of approximately 200kD which is expressed by cells of haemapoietic origin. |
Formulation | containing 0.09% Sodium Azide State: Supernatant State: Liquid Tissue Culture Supernatant |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Background | CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc. |
Synonyms | Leukocyte common antigen, L-CA, PTPRC, T200, LCA |
Reference Data |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Regenerative Features of Adipose Tissue for Osteoarthritis Treatment in a Rabbit Model: Enzymatic Digestion Versus Mechanical Disruption
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International Journal of Molecular Sciences
,PubMed ID 31146351
|
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