CTLA4 Mouse Monoclonal Antibody [Clone ID: BNI3]

Specifications

Product Data
Clone Name	BNI3
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: Use 10µl of Neat-1/10 diluted antibody to label 10e6 cells in 100µl. Immunohistochemistry on Frozen Sections: 5-50 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human CTLA-4/human IgG heavy chain fusion protein. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/X63-Ag8.653 myeloma cell line.
Specificity	This antibody recognises the CD152 cell surface antigen, also known as CTLA-4 (cytotoxic T-lymphocyteassociated antigen 4).
Formulation	PBS containing 0.09% Sodium Azide as preservative and 0.1% BSA as stabilizer. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cytotoxic T-lymphocyte associated protein 4
Database Link	Entrez Gene 1493 Human UniProt ID P16410
Background	CD152 is a 45kD glycoprotein, expressed normally as a disulphide-linked homodimer. It is expressed transiently on the surface of T cells following activation (peaking at 3 days), but is often present with the cytoplasm. CD152 is a ligand for CD80 and CD86, and is important in cellular interactions during the immune response.
Synonyms	CTLA-4
Reference Data

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