CD45 (PTPRC) (CD45RO) Mouse Monoclonal Antibody [Clone ID: UCHL1]
CAT#: SM1117S
CD45 (PTPRC) (CD45RO) mouse monoclonal antibody, clone UCHL1, Supernatant
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CNY 5,236.00
货期*
4周
规格
Specifications
Product Data | |
Clone Name | UCHL1 |
Applications | IHC |
Recommend Dilution | Immunohistochemistry on Frozen Sections. Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/100 Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended. Use Polymer anti Mouse/Rabbit IgG as a detection system. Recommended Positive Control: Tonsil or lymph node. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Interleukin-2-dependent Human T lymphocytes. |
Specificity | UCHL-1 reacts with mature activated T cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. Shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. It rarely stains B cell lymphomas. Cellular Localization: Membranous. |
Formulation | State: Supernatant State: Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C. |
Gene Name | protein tyrosine phosphatase, receptor type C |
Database Link | |
Background | CD45RO is a single chain transmembraneous glycoprotein which represents the low molecular weight isoform of the Leucocyte Common Antigen (LCA). It expressed on most thymocytes, monocytes, macrophages and granulocytes. It is not expressed on normal B lymphocytes. Intrathymic T cell maturation progresses from CD45RA-/CD45RO+ to CD45RA+/CD45RO-; while peripheral T cell maturation progresses from CD45RA+/CD45RO- to CD45RA-/CD45RO+. |
Synonyms | PTPRC, Leukocyte common antigen, L-CA, T200 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
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