CD41 (ITGA2B) Mouse Monoclonal Antibody [Clone ID: PM6/248]

Specifications

Product Data
Clone Name	PM6/248
Applications	FC
Recommend Dilution	Flow Cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human platelet plasma membrane. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity	This antibody recognises the CD41 cell surface antigen. It has not been established if clone PM6/248 recognises free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognised is dependent upon an intact CD41/61 complex.
Formulation	PBS, pH 7.4 containing 009% Sodium Azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE)
Reconstitution Method	Restore with distilled water.
Purification	Ion Exchange Chromatography.
Conjugation	PE
Storage Condition	Prior to and following reconstitution store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	integrin subunit alpha 2b
Database Link	Entrez Gene 3674 Human UniProt ID P08514
Background	CD41 is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.
Synonyms	Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.