CD41 (ITGA2B) Mouse Monoclonal Antibody [Clone ID: PM6/248]

Specifications

Product Data
Clone Name	PM6/248
Applications	FC
Recommend Dilution	Flow cytometry: 1/100 - 1/200; Use 10µl of the suggested working dilution to label 100µl human whole blood.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human platelet plasma membrane. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Specificity	This antibody recognises the CD41 cell surface antigen. It has not been established if clone PM6/248 recognises free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognised is dependent upon an intact CD41/61 complex.
Formulation	State: Azide Free State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	integrin subunit alpha 2b
Database Link	Entrez Gene 3674 Human UniProt ID P08514
Background	CD41 is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.
Synonyms	Integrin alpha-IIb, GP2B, ITGAB, GPalpha IIb
Reference Data

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