CD15 Mouse Monoclonal Antibody [Clone ID: TG-1]

CAT#: SM1089B

CD15 mouse monoclonal antibody, clone TG-1, Biotin



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CNY 9,356.00


货期*
5周

规格
    • 200 ug

Product images

Specifications

Product Data
Clone Name TG-1
Applications FC
Recommend Dilution In flow cytometry (1.0 x 10e6 cells ), IFA and IHC (acetone-fixed frozen sections). May be used for enumerating mature granulocytes in peripheral blood.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Thymocyte glycoprotein fraction adsorbed to Con A and eluted with 0.1 M glucose
Specificity Recognizes a (Mr 156 kDa) cell surface glycoprotein expressed on virtually all peripheral blood granulocytes.(1,2,3). Anti-CD15 has virtually no reactivity with T or B cells.(1,2,3).
Formulation 0.01 M PBS, pH7.2 containing 1 % BSA as stabilizer and 0.09 % Sodium azide as preservative
Label: Biotin
State: Liquid purified Ig fraction
Concentration lot specific
Purification Ion exchange chromatography and gel filtration
Conjugation Biotin
Storage Condition Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! Should this product contain a precipitate we recommend microcentrifugation before use.
Background The CD15 antigen is expressed on approximately 90% human circulating granulocytes (membranes and granules), 30 to 60% of circulating monocytes and is absent from normal lymphocytes. CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin's disease, on T cell lymphomas including mycosis fungoides and on some leukemias. Outside the hematopoietic system, CD15 expression is described in certain normal and neoplastic epithelial cells and in astrocytes. At least 5 major CD15 antigens (105, 135, 165, 185, 220 kDa) are present on the surface membranes of polymorphonuclear cells. The hapten occurs also in glycolipids. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.
Synonyms Lewis X, X-Hapten, Lacto-N-Fucopentaose III, Stage-Specific Embryonic Antigen, SSEA1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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