C Reactive Protein (CRP) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IP, WB
Recommend Dilution	Suitable for Immunoblotting (Western or Dot blot), ELISA, Immunoprecipitation and most immunological methods requiring high titer and specificity. Recommended Dilutions: ELISA: 1/20,000-1/100,000. Western Blot: 1/2,000-1/10,000. Immunohistochemistry: 1/1,000-1/5,000.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Capsular Reactive Protein (CRP) from Human Serum.
Specificity	This product was prepared from monospecific antiserum by a Delipidation and Defibrination. Assay by Immunoelectrophoresis resulted in a single precipitin arc against purified and partially purified Capsular Reactive Protein (CRP) [Human Serum]. Cross reactivity against Capsular Reactive Protein (CRP) from other tissues and species may occur but have not been specifically determined.
Formulation	0.01M Sodium Phosphate, 0.15M Sodium Chloride, pH 7.2 without preservatives State: Serum State: Lyophilized Stabilizer: None
Reconstitution Method	Restore with 2.0 ml of deionized water (or equivalent).
Concentration	lot specific
Purification	Delipidation and Defibrination.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Dilute only prior to immediate use. Centrifuge product if not completely clear after standing at room temperature. Avoid repeated freezing and thawing.
Gene Name	C-reactive protein, pentraxin-related
Database Link	Entrez Gene 1401 Human UniProt ID P02741
Background	The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa; physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.
Synonyms	PTX1, C Reactive Protein, Pentraxin-related
Reference Data

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