IL22 Rabbit Polyclonal Antibody

CAT#: PP1224B2

IL22 rabbit polyclonal antibody, Biotin

Conjugation: Unconjugated Biotin



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CNY 4,790.00


货期*
5周

规格
    • 50 ug

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Specifications

Product Data
Applications ELISA, WB
Recommend Dilution Direct ELISA: To detect Human IL-22 by direct ELISA (using 100 µl/well) a concentration of ~1.0 µg/ml of this antibody is required. The Biotinylated antibody allows the detection of at least 0.2-0.4 ng/well of recombinant Human IL-22.
Sandwich ELISA: To detect Human IL-22 by Sandwich ELISA (using 100 µl/well) a concentration of 0.25-1.0 µg/ml of this antibody is required. The Biotinylated antibody, in conjuction with anti-Human IL22 (PP1224P1 or PP1224P2) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human IL-22.
Western blot: To detect Human IL-22 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant Human IL-22 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Highly pure (>98%) E.coli derived recombinant Human IL-22 (hIL-22).
Specificity Recognizes Human Interleukin-22 (IL-22).
Formulation PBS, pH 7.2 without preservatives.
Label: Biotin
State: Lyophilized (sterile filtered) purified Ig fraction.
Reconstitution Method Restore with sterile PBS solution containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Purification Affinity Chromatography.
Conjugation Biotin
Storage Condition Store the antibody prior to reconstitution at -20°C.
Following reconstitution the antibody can be stored at 2-8°C for one month or at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name interleukin 22
Background IL22 is a cytokine structurally related to IL10 and is upregulated in activated T cells. IL22 signals through a receptor complex that includes CRF2-4 and a new member of the class II cytokine receptor family (also known as the interferon receptor family), IL22R. CRF2-4 has previously been demonstrated to be a functional component of the IL-10 signaling complex.
IL22 is able to suppress IL4 production; this may have therapeutic potential, particularly in the treatment of asthma.
Synonyms IL-22, ILTIF, Cytokine Zcyto18
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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