Calcitonin (CALCA) Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunohistochemistry on Paraffin Embedded or Frozen Tissue Sections. Immunofluorescence Microscopy: Dilute 1/800-1/1200 Using FITC with overnight incubation at 2-8°C. Recommended Positive Control: Frozen sections of Rat colon.
Reactivity	Human, Mouse, Rat
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic Calcitonin Gene Related Peptide (Peninsula), conjugated to BSA.
Specificity	This antibody reacts with Calcitonin gene-related peptide (CGRP). Absoprtion with 10-100 µg CGRP per ml diluted antiserum abolishes the staining while Calcitonin does not. It does not cross-react with Amylin (IAPP).
Formulation	State: Serum State: Lyophilized undiluted Serum
Reconstitution Method	Restore in 100 µl distilled water.
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	calcitonin related polypeptide alpha
Database Link	Entrez Gene 796 Human UniProt ID P06881
Background	The CGRP-sequence was predicted from the corresponding mRNA. CGRP is present in the C-cells of the thyroid and in nerves, in both brain and periphery, particularly within the sensory system. CGRP is a potent vasodilator, probably involved in neurogenic inflammation. Medullary carcinomas of the thyroid contain large amounts of CGRP.
Synonyms	Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.