Synaptophysin (SYP) Rabbit Monoclonal Antibody [Clone ID: SP11]

Specifications

Product Data
Clone Name	SP11
Applications	IHC
Recommend Dilution	Immunohistochemistry on formalin-fixed paraffin embedded sections: Use at 1/100 in an ABC method (30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Pancreas.
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human Synaptophysin
Specificity	This antibody recognizes a protein of 38 kDa, identified as synaptophysin. It labels normal neuroendocrine cells of adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, gastrointestinal mucosa, Paneths cells in the gastrointestinal tract and of gastric parietal cells. Neurons in the brain, spinal cord, and retina are also labeled. In combination with anti-chromogranin A and anti-NSE, Ab to synaptophysin is very useful in the identification of normal neuroendocrine cells and neuroendocrine neoplasms. Cellular Localization: Cytoplasmic.
Formulation	State: Supernatant State: Liquid tissue culture supernatant containing sodium azide as preservative
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	synaptophysin
Database Link	Entrez Gene 6855 Human UniProt ID P08247
Synonyms	Neuroendocrine Marker
Reference Data
Protein Families	Secreted Protein, Transmembrane

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