Vegfa Rabbit Polyclonal Antibody
CAT#: DP3520B
Vegfa rabbit polyclonal antibody, Biotin, Aff - Purified
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CNY 3,890.00
货期*
5周
规格
Specifications
Product Data | |
Applications | ELISA |
Recommend Dilution | ELISA: 1-10 µg/ml. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Highly pure (> 95%) recombinant Murine VEGF164 Dimer derived from insect cells |
Specificity | The antibody recognizes VEGF-A. |
Formulation | PBS, pH 7.2 Label: Biotin State: Aff - Purified State: Lyophilized purified IgG fraction Stabilizer: 50x BSA Preservative: 0.02% Sodium Azide |
Reconstitution Method | Restore in sterile water to a concentration of 0.1-1.0 mg/ml. Centrifuge vial prior to opening. |
Purification | Antigen Affinity Chromatography |
Conjugation | Biotin |
Storage Condition | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Gene Name | vascular endothelial growth factor A |
Database Link | |
Background | Mouse Vascular Endothelial Growth Factor164 (VEGF164), a 24 kDa protein consisting of 164 amino acid residues, is produced as a homodimer. VEGF164 is a polypeptide growth factor and a member of the platelet-derived growth factor family. It is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. Two high-affinity tyrosine kinase receptors for VEGF164 have been identified, VEGFR-1 (FLT-1), and VEGFR-2 (Flk-1). In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo and is also a chemoattractant for monocytes and endothelial cells. At least three different proteins are generated by differential splicing of the mouse VEGF gene: VEGF120, VEGF164 and VEGF188. The most abundant form is VEGF164. Whereas VEGF120 and VEGF164 are secreted proteins, VEGF188 is strongly cell-associated. In addition, the isoforms VEGF164 and VEGF188 bind to heparin with high affinity. A related protein of VEGF is placenta growth factor (PlGF) with about 53% homology and VEGF-B with similar biological activities. |
Synonyms | VEGFA, VEGF, VPF, Vascular endothelial growth factor A, Vascular permeability factor |
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