Granzyme B (GZMB) Rabbit Polyclonal Antibody
CAT#: DP105-05
Rabbit polyclonal anti-Granzyme B (GZMB) antibody, Purified
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CNY 7,051.00
货期*
5周
规格
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic peptide from the N-terminus of human Granzyme B. |
Formulation | 10 mM Citrate Buffer, pH 6.0 containing Sodium Azide as preservative. |
Purification | Liquid purified Ig fraction. Purified |
Conjugation | Unconjugated |
Predicted Protein Size | ~25.5 kDa |
Gene Name | granzyme B |
Database Link | |
Background | Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned. Human granzymes B is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. This antibody is useful in the localization of granzyme B containing lytic granules and for the characterization of activated CTLs or NK cells. |
Synonyms | C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA-1; CTLA1; CTSGL1; Fragmentin-2; Granzyme-2; GRB; HLP; SECT |
Reference Data | |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus |
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