Chromogranin A (CHGA) Mouse Monoclonal Antibody [Clone ID: NJ-5C9]

Specifications

Product Data
Clone Name	NJ-5C9
Applications	ELISA, FC, WB
Recommend Dilution	Flow cytometry: 1.2 µg/10e6 cells. ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Genetic immunisation with cDNA encoding CGA
Specificity	Recognizes Chromogranin A (CGA).
Formulation	Phosphate buffered saline, pH 7.2 State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein G.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	chromogranin A
Database Link	Entrez Gene 12652 MouseEntrez Gene 1113 Human UniProt ID P10645
Background	Chromogranin A (CgA) is a 49 kDa protein which is a member of the granin/secretogranin family of acidic glycoproteins. It is specifically expressed in all endocrine and neuroendocrine cells and plays multiple roles in the process of regulated secretion of peptide hormones and neurotransmitters (1). Owing to its over-expression in several tumors of neuroendocrine origin, CgA is of diagnostic value in classical endocrine, in hormone-negative and in neuroendocrine tumors (2).
Synonyms	Chromogranin-A, CgA, CHGA, SP-I
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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