CEACAM7 Mouse Monoclonal Antibody [Clone ID: BAC2]
CAT#: DM1207
CEACAM7 mouse monoclonal antibody, clone BAC2, Purified
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CNY 5,660.00
货期*
5周
规格
Cited in 6 publications. |
Specifications
Product Data | |
Clone Name | BAC2 |
Applications | ELISA, FC, IF, IHC |
Recommend Dilution | ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200. Flow cytometry: 1.2 µg/106 cells. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | CEACAM7/Fc fusion protein |
Specificity | This antibody recognizes CEACAM7. |
Formulation | Phosphate buffered saline, pH 7.2 without preservatives State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | carcinoembryonic antigen related cell adhesion molecule 7 |
Database Link | |
Background | CEA-related cell adhesion molecule 7 (CEACAM7, CGM2) belongs to the carcinoembryonic antigen (CEA) family (1). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts (2). CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon (2). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A domain. |
Synonyms | CGM2 |
Reference Data |
Citations (6)
The use of this Antibodies has been cited in the following citations: |
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Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence
,Fahlgren A, Baranov V, Frdngsmyr L, Zoubir F, Hammarstrvm ML, Hammarstrvm S,
Scand. J. Immunol.
,PubMed ID 14636419
[CEACAM7]
|
Deregulation of the CEACAM expression pattern causes undifferentiated cell growth in human lung adenocarcinoma cells
,Singer BB, Scheffrahn I, Kammerer R, Suttorp N, Ergun S, Slevogt H,
PLoS ONE
,PubMed ID 20090913
[CEACAM7]
|
The prevalence and nature of glycan alterations on specific proteins in pancreatic cancer patients revealed using antibody-lectin sandwich arrays
,Yue T, Goldstein IJ, Hollingsworth MA, Kaul K, Brand RE, Haab BB,
Mol. Cell Proteomics
,PubMed ID 19377061
[CEACAM7]
|
Carcinoembryonic antigen and CD44 variant isoforms cooperate to mediate colon carcinoma cell adhesion to E- and L-selectin in shear flow
,Thomas SN, Zhu F, Schnaar RL, Alves CS, Konstantopoulos K,
J. Biol. Chem.
,PubMed ID 18375392
[CEACAM7]
|
Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell adhesion molecule-1 via interaction with VEGFR-3 and Prox1
,Kilic N, Oliveira-Ferrer L, Neshat-Vahid S, Irmak S, Obst-Pernberg K, Wurmbach JH, Loges S, Kilic E, Weil J, Lauke H, Tilki D, Singer BB, Erg|n S,
Blood
,PubMed ID 17761831
[CEACAM7]
|
Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas
,Schvlzel S, Zimmermann W, Schwarzkopf G, Grunert F, Rogaczewski B, Thompson J,
Am. J. Pathol.
,PubMed ID 10666389
[CEACAM7]
|
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