CD79A Mouse Monoclonal Antibody [Clone ID: HM57]

Specifications

Product Data
Clone Name	HM57
Applications	IHC
Recommend Dilution	Immunohistochemistry on Frozen and Paraffin Sections: diluted of 1/15-1/30 in an ABC method (30-60 minutes at room temperature or overnight at 4°C) Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide comprising of 202-216 C terminal amino acids part of mb-1 protein.
Specificity	This antibody reacts specifically with B cells at the pre B cell stage.  It stains the majority of acute leukemias of precursor B cell type, B cell lymphomas, and some myelomas. The mb-1 polypeptide and B29 polypeptide forms an antigen receptor complex on the B cell, performing signal transaction and phosphorylation functions. Cellular Localization:  Cell membrane.
Formulation	State: Supernatant State: Liquid Ig fraction Stabilizer: 1% BSA Preservative: 0.05% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD79a molecule
Database Link	Entrez Gene 973 Human UniProt ID P11912
Background	It stains majority of acute leukemias of precursor B cell type, B cell lymphomas and some myelomas. The mb-1 polypeptide along with B29 polypeptide forms an antigen receptor complex on the B cell performing signal transaction and phosphorylation functions.
Synonyms	IGA, MB1, B-Cell marker
Reference Data

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