TGF beta 1 (TGFB1) Mouse Monoclonal Antibody [Clone ID: 2E6]

Specifications

Product Data
Clone Name	2E6
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot: This antibody, used at a concentration of 1-10 ng/ml, will allow visualization of 100 ng/lane of TFG-beta.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	TGF-β from human platelets
Specificity	Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12.5 kDa.) forms of TGF-beta under both non-reducing and reducing conditions respectively. This antibody recognizes both human platelet-derived and recombinant TGF-beta in ELISA.
Formulation	0.01M PBS, pH 7.0 State: Azide Free State: Lyophilized purified IgG
Reconstitution Method	Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/ml
Purification	Protein G affinity purified
Conjugation	Unconjugated
Storage Condition	Store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	transforming growth factor beta 1
Database Link	Entrez Gene 7040 Human UniProt ID P01137
Background	TGF beta 1 (Transforming Growth Factor Beta 1) is a multifunctional peptide capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed as well as non neoplastic tissues, release transforming growth factors; and essentially all cells possess a specific TGF beta 1 receptor. The multimodal nature of TGF beta 1 is seen in its ability to stimulate or inhibit cellular proliferation. TGF beta 1 plays a fundamental role in tissue growth and differentiation involvement in adipogenesis, myogenesis, chondrogenesis, osteogenesis, epithelial cell differentiation and immune cell function. The C-terminal 112 amino acids constitute the mature protein.
Synonyms	TGFB, Transforming growth factor beta-1, TGF-beta-1
Reference Data

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